#inflammageing

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Environment
fromNature
2 months ago

Daily briefing: Rookie researchers boost disruptive science

Mitochondrial DNA release may drive ageing inflammation; China pledges 7–10% emissions cuts from peak by 2035; welcoming novice researchers can boost innovation.
Science
fromNature
2 months ago

Mitochondria expel tainted DNA - spurring age-related inflammation

Mitochondria eject mtDNA containing excess harmful nucleotides, releasing it into the cytosol and activating inflammatory pathways that drive ageing-related inflammation.
Science
fromNature
2 months ago

Daily briefing: A polo-team's worth of cloned CRISPR horses

CRISPR-edited cloned polo horses spark controversy while air pollution links to Lewy body dementia and a new fat-resident immune cell contributes to inflammageing in mice.
fromNature
2 months ago

Newfound immune cell in mice hints at why inflammation spikes with old age

When injuries or infections occur, the immune system mounts a protective response by releasing cells and proteins to affected tissues. This complex cascade is called inflammation. But as we age, inflammation gradually increases and becomes persistent instead of being a state that occurs only when things go wrong. Among the cells that that help to regulate this inflammageing are a variety of macrophages - white blood cells that hoover up pathogens and cellular debris - that reside in fat tissue.
Science
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