"Mitochondria - the powerhouses of the cell - expel 'tainted' DNA into their surroundings. In mice, researchers found that the organelles spit out strands of mitochondrial DNA (mtDNA) that contained an excess of a certain type of molecular building block that can harm DNA. This genetic fly-tipping might protect the mitochondria, but free-floating mtDNA in a cell kick-starts key inflammatory pathways associated with ageing. The findings hint at mitochondria's role in 'inflammageing' - chronic inflammation that occurs as we get older."
"Chinese president Xi Jinping has announced that, by 2035, China will reduce greenhouse gas emissions by 7-10% from their peak level. In 2020, Xi pledged that China's CO 2 emissions would reach their peak before 2030, a milestone some researchers think might have been reached already. As the largest emitter in the world, the pace of China's cuts will have profound global impact:"
Mitochondria release strands of mitochondrial DNA (mtDNA) containing excess mutagenic molecular building blocks into their surroundings. In mice, expelled mtDNA activates inflammatory pathways associated with ageing, implicating mitochondrial DNA release in chronic 'inflammageing'. Chinese president Xi Jinping announced that, by 2035, China will reduce greenhouse-gas emissions by 7–10% from their peak level, a commitment that could materially affect global emissions but leaves room for short-term increases and may not suffice to keep warming within 1.5–2 °C. An analysis of over 28 million articles found that research teams including beginner scientists with few prior publications produce more disruptive, innovative work. Engineering education is being reimagined.
#mitochondrial-dna #inflammageing #greenhouse-gas-emissions #china-climate-policy #research-innovation
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