#gene editing
#gene editing

Mike Curtis

eGenesis is using CRISPR to edit pig genes for safer human organ transplants. [ more ]

Mail Online

OMG science

New AI can CHANGE human genes to cure even the rarest of diseases

AI-designed gene editing system OpenCRISPR-1 reduces off-target editing by 95%, offering potential for precise genetic disease cures. [ more ]

Futurism

3 weeks ago

Artificial intelligence

Startup Uses AI to Edit Human DNA

Profluent uses AI to edit human DNA, creating potential groundbreaking gene editors for disease cures. [ more ]

Engadget

Researchers developed a gene-editing technology that reduces 'bad' cholesterol

A gene-editing treatment called VERVE-101 showed promising results in reducing cholesterol levels in patients with hereditary conditions.

The treatment used CRISPR editing techniques to turn off a cholesterol-raising gene in the liver, resulting in lower levels of LDL-C.

While the therapy has the potential to disrupt current high cholesterol treatments, further studies and FDA approval are needed before it can be widely available. [ more ]

Ars Technica

Crispr gene editing shown to permanently lower high cholesterol

Researchers have shown that a single infusion of a novel gene-editing treatment can reduce cholesterol in a small test on people.

The gene-editing treatment aims to permanently lower cholesterol by using Crispr to edit a gene in the liver.

Preliminary results of the experiment were presented at the American Heart Association's annual meeting. [ more ]

WIRED

A Single Infusion of a Gene-Editing Treatment Lowered High Cholesterol

Researchers have shown that a single infusion of a gene-editing treatment can reduce cholesterol levels in people.

The treatment aims to permanently lower cholesterol by using Crispr to edit a gene in the liver, and initial results show significant reductions in LDL cholesterol.

Gene editing could provide a lasting option for treating hereditary high cholesterol, replacing the need for long-term medication. [ more ]

Inverse

Goodbye Statins? New Gene Editing Therapy Slashes High Cholesterol

A novel gene editing therapy using base editing lowered "bad" cholesterol levels in individuals with FH by as much as 55 percent.

The therapy could potentially provide a single-course treatment option for deep LDL lowering for decades without the need for daily pills or intermittent injections. [ more ]

www.nytimes.com

New Gene Editing Treatment Cuts Dangerous Cholesterol in Small Study

Gene editing treatment shows promise in lowering cholesterol levels in patients with severe heart disease

Treatment has the potential to transform preventive cardiology [ more ]

morecholesterol

www.dw.com

1 week ago

OMG science

CRISPR gene editing trial treats inherited blindness DW 05/06/2024

CRISPR-Cas9 gene editing restored vision in people with rare inherited blindness, improving sight without serious side effects. [ more ]

RealAgriculture.com

1 week ago

Canada news

RealAg Radio: Gene-editing, seed regulatory modernization, and GREET model implications on canola, May 8, 2024

The episode covers topics on gene editing, seed regulatory modernization, canola industry impact, and water rationing in Southern Alberta. [ more ]

RealAgriculture.com

Canada news

Health Canada issues final decision, clearing regulatory pathway for gene-edited crops

Gene-edited crops in Canada now considered non-novel, treated like traditional breeds. [ more ]

RealAgriculture.com

5 days ago

Deliverability

RealAg Radio: Conservation easements, spring rainfall, and switching corn hybrids, May 13, 2024

Discussion on moisture levels, corn hybrids, gene-editing, and conservation easements in agriculture. [ more ]

Nature

Artificial intelligence

AI & robotics briefing: What running robots tell us about gaits

AI is used to design new gene-editing tools like CRISPR proteins, expanding capabilities beyond natural systems.

Researchers have adapted deep learning transformers for quantum computers, showing potential accuracy benefits over classical models. [ more ]

www.theguardian.com

3 months ago

Europe politics

Nobel laureates call on EU to relax rules on genetic modification

34 Nobel prize winners are urging the EU to relax rules on genetic modification before a key vote on gene editing.

They argue that gene editing techniques could make crops more resistant to disease and extreme weather events caused by climate change. [ more ]

WIRED

4 months ago

A Gene-Edited Pig Liver Was Attached to a Person-and Worked for 3 Days

Scientists used gene editing to make 69 genetic edits to a pig, including knocking out three pig genes and inserting seven human genes.

Previous attempts with unmodified pig livers failed within hours, but the pig livers with genetic edits in the Penn study showed stable blood flow and no signs of inflammation. [ more ]

WSJ

FDA Approves World's First Crispr Gene-Editing Drug for Sickle-Cell Disease

The US has approved the world's first medicine using Crispr technology.

Crispr technology has the potential to treat genetic conditions that are difficult to treat. [ more ]

The Atlantic

The CRISPR Era Is Here

Gene-editing technology CRISPR has successfully treated a patient with sickle-cell disease, providing hope for future treatments.

The treatment resulted in the patient living virtually symptom-free, with 29 out of 30 eligible patients experiencing zero pain crises after treatment. [ more ]

MedCity News

U.K. Is First to Approve a CRISPR-Based Therapy, Covering Two Blood Disorders

The UK has authorized a gene-editing medicine for treating sickle cell disease and beta thalassemia, marking the first approval worldwide for a therapy based on CRISPR technology.

The therapy, known as Casgevy, involves editing a gene in a patient's stem cells to produce high levels of fetal hemoglobin.

Casgevy offers a potentially curative treatment option for these inherited blood disorders, reducing the need for chronic therapies and blood transfusions. [ more ]

Engadget

UK authorizes first gene therapy for treating sickle cell disease

The UK's MHRA has approved the use of a gene-editing therapy for patients with sickle cell disease and beta thalassemia.

The therapy, called Casgevy, is the first-ever approved therapy that uses CRISPR-based gene editing technology.

The therapy has shown high efficacy in relieving severe pain associated with these blood disorders and could potentially replace the current standard of care. [ more ]

www.nytimes.com

F.D.A. Approves Sickle Cell Treatments, Including One That Uses CRISPR

The Food and Drug Administration has approved the first gene editing therapy and conventional gene therapy for sickle cell disease.

Obstacles to treatment include limited access to authorized medical centers, individualized procedures, and high costs. [ more ]

www.fastcompany.com

The U.K. approved its first CRISPR gene-editing drugand the U.S. is expected to follow

U.K. regulators have approved the first-ever CRISPR gene-editing drug for the treatment of sickle cell disease and beta thalassemia.

The therapy has shown success in clinical trials and is expected to reach the U.S. by the end of the year.

The gene editing treatment modifies stem cells to boost the production of functional hemoglobin, providing a fix at the DNA level. [ more ]

www.nytimes.com

Sickle-Cell Treatment Created With Gene Editing Wins U.K. Approval

Regulators in Britain have approved the first treatment derived from CRISPR, called Casgevy, for sickle-cell disease and beta thalassemia.

About 2,000 patients in Britain are expected to be eligible for Casgevy treatment.

The FDA is expected to approve Casgevy for sickle-cell patients in the US in early December. [ more ]

www.npr.org

For the first time, gene-editing provides hints for lowering cholesterol

Preliminary results show that gene-editing can reduce high cholesterol levels in patients with a genetic condition.

More research is needed to confirm the safety and effectiveness of the treatment.

This could potentially provide a new way to prevent heart attacks and strokes. [ more ]

www.npr.org