#functional-genomics

[ follow ]
Science
fromwww.nature.com
1 week ago

How Key Changes to the Pelvis Helped Humans Walk Upright

Two evolutionary embryonic changes in pelvic cartilage and bone enabled bipedal walking and birth of large-brained infants in early humans.
fromNature
1 week ago

How humans became upright: key changes to our pelvis found

Now, researchers have mapped the key structural changes in the pelvis that enabled early humans to first walk on two legs and accommodate giving birth to a big-brained baby. The study, published in Nature on 27 August, compared the embryonic development of the pelvis between humans and other mammals. They found two key evolutionary steps during embryonic development - related to the growth of cartilage and bone in the pelvis - which put humans on a separate evolutionary path from other apes.
Science
Science
fromNature
1 month ago

Precisely defining disease variant effects in CRISPR-edited single cells - Nature

Genome-wide association studies reveal complex trait loci, but functional assignment of non-coding variants remains a challenge requiring genomic editing.
[ Load more ]