Neutral atoms are a promising platform for quantum science, enabling advances in areas ranging from quantum simulations13 and computation410 to metrology, atomic clocks1113 and quantum networking1416. While atom losses typically limit these systems to a pulsed mode, continuous operation1722 could significantly enhance cycle rates, remove bottlenecks in metrology23, and enable deep-circuit quantum evolution through quantum error correction24,25. Here we demonstrate an experimental architecture for high-rate reloading and continuous operation of a large-scale atom array system while realizing coherent storage and manipulation of quantum information.