#clinical trials

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Medicine
fromwww.scientificamerican.com
1 day ago

New Hope in Alzheimer's Research: A Special Report

Scientific advances are producing diverse diagnostic and treatment options for Alzheimer's, including approved amyloid-targeting therapies, numerous trials, and lifestyle interventions.
Medicine
fromBusiness Insider
3 days ago

Sam Altman's longevity startup is testing a pill for a younger brain

Retro Biosciences aims to reverse age-related decline by reviving autophagy with experimental pill RTR242, targeting first human dosing by the end of 2025.
fromwww.scientificamerican.com
5 days ago

Why Intermittent Fasting May Do More Harm Than Good

Recent headlines warning of concerns such as heart risks or danger to teenagers have put a new spotlight on a diet trend that has long been the popular epitome of a healthy lifestyle: intermittent fasting. Intermittent fasting's image has been deeply tarnishedand quite rightly so, says Stefan Kabisch, a physician at the endocrinology and metabolic medicine department at ChariteUniversity Medicine Berlin. The hype was never really backed up by good data in humans.
Science
fromwww.theguardian.com
6 days ago

Britain is a terrible place' to sell medicines, says drug firm executive

We've still got the best universities, we've got some of the best scientists in the world, but it's not a good place to do the development work for medicines. It's an expensive place to operate, and it's a terrible place to sell medicines.
Medicine
fromLos Angeles Times
1 week ago

Commentary: With recent advances, it's 'a very exciting time' for dementia researchers

There are no cures yet for dementia, an umbrella term for cognitive disorders, of which Alzheimer's is the most common. But thanks to advances in recent years, drugs can treat some symptoms of mild and even moderate impairment, and with the number of dementia cases in the U.S. expected to double by 2060 as the population ages and people live longer, there's hope for continued progress.
Medicine
#hepatitis-b
#psychedelics
Cancer
fromNature
4 weeks ago

Immunotherapy using CAR T cells shows promising long-term outcomes for people with the blood cancer myeloma

CAR T cell therapy demonstrates significant long-term success in treating myeloma, with a third of patients showing no detectable cancer after five years.
Health
fromPsychology Today
4 weeks ago

Future of Cancer Treatment May Lie in Combination Therapy

Combination regimens for cancer treatment generally outperform single treatments and can improve personalization and effectiveness.
#clinical-trials
fromNature
3 months ago
Science

Daily briefing: NIH foreign-grant cuts could leave thousands without care worldwide

fromwww.theguardian.com
4 months ago
Women in technology

Male bias in medical trials risks women's lives. But at least the data gap is finally being addressed | Caroline Criado Perez

fromNature
3 months ago
Science

Daily briefing: NIH foreign-grant cuts could leave thousands without care worldwide

Women in technology
fromwww.theguardian.com
4 months ago

Male bias in medical trials risks women's lives. But at least the data gap is finally being addressed | Caroline Criado Perez

The MHRA has recognized a significant gender imbalance in clinical trials, highlighting a critical issue in women's health research.
Women
fromwww.theguardian.com
4 months ago

The Guardian view on bias in medical research: disregard for women's health belongs in the past | Editorial

Significant gender disparities remain in clinical trial participation, with more trials focusing on men's health.
Women's health continues to be underrepresented in medical research despite prior advocacy.
fromPsychology Today
1 month ago

When AI Starts Seeing What Doctors See

The simple truth is that medicine is always multimodal. A physician's mind doesn't travel in a straight line, drifting from the patient's story to the CT image, lab values, and clues in a physical exam.
Health
#weight-loss
Wearables
fromwww.theguardian.com
5 months ago

New daily weight-loss pill shows success at clinical trial

Orforglipron is a promising daily weight-loss pill that effectively aids in weight loss and reduces blood sugar in individuals with type 2 diabetes.
Wearables
fromwww.theguardian.com
5 months ago

New daily weight-loss pill shows success at clinical trial

Orforglipron is a promising daily weight-loss pill that effectively aids in weight loss and reduces blood sugar in individuals with type 2 diabetes.
#psychedelic-therapy
fromNews Center
1 month ago

'Dancing Molecules' Treatment Receives FDA Orphan Drug Designation - News Center

"Dancing molecules," the promising new treatment for acute spinal cord injuries developed at Northwestern University, has received Orphan Drug Designation from the U.S. Food and Drug Administration (FDA).
Science
#drug-development
Science
fromwww.scientificamerican.com
1 month ago

Male Birth Control Pill to Stop Sperm Production Passes Safety Test

YCT-529 is a hormone-free pill that blocks a vitamin A metabolite to stop sperm production, deemed safe for human use in trials.
#parkinsons-disease
fromNature
5 months ago
Alternative medicine

Daily briefing: The biggest single piece of meat ever grown in the lab

Alternative medicine
fromNature
5 months ago

'Big leap' for Parkinson's treatment: symptoms improve in stem-cells trials

Early-stage stem cell trials show promise for treating Parkinson's disease by replacing lost dopamine-producing neurons.
fromNature
5 months ago
Alternative medicine

Daily briefing: The biggest single piece of meat ever grown in the lab

Alternative medicine
fromNature
5 months ago

'Big leap' for Parkinson's treatment: symptoms improve in stem-cells trials

Early-stage stem cell trials show promise for treating Parkinson's disease by replacing lost dopamine-producing neurons.
Science
fromNature
2 months ago

Found: a human gut microbe that makes cancer therapy more effective in mice

A gut bacterium can enhance cancer drug effectiveness by stimulating immune cells in mice, with plans for human trials.
fromSilicon Canals
2 months ago

Barcelona's Biorce raises 5M: CEO Pedro Coelho on tackling clinical trial delays with AI, US expansion, and hiring plans - Silicon Canals

Biorce is exactly the kind of pioneering company we're here to back. They're combining deep sector expertise with cutting-edge AI to solve what truly matters.
Healthcare
#ai-in-healthcare
fromHackernoon
5 months ago
Artificial intelligence

How AI Agents Could Have Supercharged Pfizer's COVID-19 Vaccine Development | HackerNoon

Artificial intelligence
fromHackernoon
5 months ago

How AI Agents Could Have Supercharged Pfizer's COVID-19 Vaccine Development | HackerNoon

AI agents could accelerate vaccine development and drug discovery processes significantly.
Through active collaboration and learning, AI agents transform traditional procedures in healthcare research.
fromMiami Herald
2 months ago

A paralyzed patient at UM just got Elon Musk's brain chip. Here are 5 takeaways

The Neuralink chip, known as the Link or Telepathy, was implanted by surgeons at the University of Miami Miller School of Medicine, marking the first such procedure at a Miami hospital. The chip allows RJ to wirelessly control a computer, as demonstrated by his ability to play video games using only his mind.
Artificial intelligence
#immunotherapy
Cancer
fromArs Technica
4 months ago

A new era in cancer therapies is at hand

New cancer therapies are advancing beyond traditional immunotherapy, providing safer, more effective treatment options for various tumor types.
Cancer
fromArs Technica
4 months ago

A new era in cancer therapies is at hand

New cancer therapies are advancing beyond traditional immunotherapy, providing safer, more effective treatment options for various tumor types.
Science
fromFortune
2 months ago

Google DeepMind has grand ambitions to 'cure all diseases' with AI. Now, it's gearing up for its first human trials

Isomorphic Labs is set to launch human trials of AI-designed drugs, leveraging advancements from DeepMind's AlphaFold for drug discovery.
fromwww.theguardian.com
2 months ago

Is exercise really better than drugs for cancer remission? It's an appealing idea but it's misleading | Devi Sridhar

The study highlighted that combining structured exercise with chemotherapy can improve overall health outcomes in colon cancer recovery, showing that exercise should complement medical treatments.
Health
US news
fromNature
2 months ago

Harvard vs Trump: what this epic battle means for science

Government actions jeopardize university research funding and threaten scientific progress at Harvard.
fromwww.bbc.com
2 months ago

Low aspirin dose 'cuts cancer risk in some people'

Prof Sir John Burn from Newcastle University stated that a study involving 1,879 individuals with Lynch syndrome shows a low dose of 75mg aspirin effectively reduces cancer risk as larger doses.
Cancer
fromNature
2 months ago

Obesity drugs show promise treating a new ailment: migraine

In a small study, the drug liraglutide reduced monthly migraine episodes by nearly half among people with obesity who experience the headache-inducing condition.
Alternative medicine
#diabetes
#cancer-treatment
fromThe Washington Post
3 months ago
US news

His custom cancer therapy is in an NIH freezer. He may not get it in time.

Staff cuts at NIH delayed critical cancer treatment for a patient, highlighting the real-world impact of administrative decisions on health outcomes.
fromwww.theguardian.com
3 months ago
Cancer

Immunotherapy trial helps cancer patients with tumours live 40% longer

Car T-cell therapy significantly prolongs survival in cancer patients by approximately 40% compared to standard treatments.
Cancer
fromwww.theguardian.com
3 months ago

Immunotherapy trial helps cancer patients with tumours live 40% longer

Car T-cell therapy significantly prolongs survival in cancer patients by approximately 40% compared to standard treatments.
Cancer
fromwww.theguardian.com
3 months ago

UK-wide drug trial hailed as a milestone' in leukaemia treatment

A UK trial found a chemotherapy-free treatment for leukaemia that improves outcomes for patients, suggesting a significant shift in treatment approaches.
fromBoston.com
3 months ago

Boston drug company laying off 125 employees in R.I.

Business Vertex says the layoffs are due to the discontinuation of a Type 1 diabetes study.
NYC startup
#biotech
#cancer-research
Cancer
fromNature
3 months ago

Cancer fighting CAR-T cells show promising results for hard-to-treat tumours

CAR-T-cell therapy shows promise for treating solid tumors, potentially revolutionizing cancer treatment beyond blood cancers.
Cancer
fromwww.theguardian.com
3 months ago

Exercise better than drugs' after cancer treatment, international trial finds

Exercise can significantly reduce the risk of cancer recurrence and mortality, outperforming many standard drugs post-treatment.
Cancer
fromwww.nytimes.com
4 months ago

Immunotherapy Drug Spares Cancer Patients From Grisly Surgeries and Harsh Therapies

Dostarlimab immunotherapy shows promise for treating solid tumors with fewer severe side effects, achieving remarkable tumor regression in clinical trials.
Cancer
fromNature
4 months ago

Clinical trials by the numbers

Cancer is the second leading cause of death globally, requiring urgent advancements in diagnosis and treatment to keep pace with the rising incidence.
Emerging biopharmaceutical companies are increasingly dominating the oncology clinical trial landscape, reflecting their growing importance in cancer research.
#vaccines
Non-profit organizations
fromNature
3 months ago

NIH grant cuts will axe clinical trials abroad - and could leave thousands without care

The NIH's new policy banning foreign subawards threatens ongoing international clinical trials, causing uncertainty for researchers and participants.
fromNews Center
3 months ago

New Scoring System Improves Colorectal Cancer Risk Prediction - News Center

The ARCAD database is a wonderful example of collaborative efforts around the world to create large patient-derived datasets that enable expanded research opportunities beyond the initial question addressed in the original design of a clinical trial.
Cancer
Cancer
fromenglish.elpais.com
3 months ago

Experimental drug fights lung cancer in nonsmokers: I feel like I did when I was healthy'

Lung cancer is increasingly diagnosed in non-smokers, particularly women, presenting new medical challenges.
Medicine
fromNature
3 months ago

Brain drugs can now cross the once impenetrable blood-brain barrier

Gordon's sons have new hope due to innovative treatments for Hunter syndrome, unlike her brothers who faced dire outcomes.
#pediatric-healthcare
Public health
fromCbsnews
3 months ago

Who can get updated COVID vaccines this fall? FDA will OK for high-risk groups, calls for new clinical trials

FDA is raising standards for COVID-19 booster approvals, focusing on high-risk groups.
Future vaccine updates for low-risk individuals will require robust clinical trials.
Parenting
fromArs Technica
4 months ago

The remarkable timeline of a custom gene-editing therapy to save a newborn

KJ received groundbreaking gene-editing therapy at just six months old, showcasing rapid advancements in clinical trial processes.
fromSilicon Canals
4 months ago

Dutch-based Hy2Care raises 4.5M from EIC, others for US clinical trial and commecial expansion - Silicon Canals

This funding round gives us the momentum needed to take the next big step in our journey, launching U.S. clinical trials and supporting our European commercialization strategy.
European startups
Data science
fromHackernoon
4 months ago

Efficient Bayesian Power Prior Survival Modeling with BayesPPDSurv | HackerNoon

The BayesPPDSurv package enhances clinical trial design by integrating historical data for more efficient time-to-event analysis.
#bayesian-statistics
Women
fromPsychology Today
4 months ago

Women With Alcohol Use Disorder Have A Different Disease

Alcohol use disorder (AUD) in women necessitates sex-specific treatment strategies due to distinct neurobiological and psychological differences from men.
Wearables
fromwww.mercurynews.com
4 months ago

Zepbound trims more belly fat than Wegovy, study shows

Eli Lilly's Zepbound outperformed Novo Nordisk's Wegovy in a recent study, showing superior weight loss and waist circumference reduction.
Alternative medicine
fromtime.com
4 months ago

Which Weight-Loss Drug Works the Best?

Zepbound shows superior weight loss compared to Wegovy in a recent clinical trial, influencing treatment decisions for obesity management.
fromPsychology Today
4 months ago

Historical Abuses and Community-Based Participatory Research

The past research abuses at the Addiction Research Center (ARC) are emblematic of a broader, systemic issue of medical racism in U.S. healthcare.
Online Community Development
fromSFGATE
4 months ago

Bay Area biotech company slashes staff after losing $655 million in value

Pliant Therapeutics announced a 45% workforce reduction, equivalent to about 75 employees, to extend its cash runway after halting a critical Phase 2b trial over safety concerns.
Startup companies
fromwww.nytimes.com
4 months ago

Wegovy Can Treat a Dangerous Liver Disease, Study Finds

After 72 weeks, nearly 63 percent of those who received semaglutide injections and around 34 percent of those on placebo shots saw their liver condition improve.
Medicine
OMG science
fromNature
4 months ago

The dismantling of US science: can it survive Trump 2.0?

Trump's policies may irreversibly reshape US science funding and research, sparking fears for the future of scientific advancement.
fromSilicon Canals
4 months ago

Ghent-based Azalea Vision raises 9M to advance eye care with real-time adaptive smart lenses - Silicon Canals

Azalea Vision's first closing of its €15M Series A funding round enables the clinical trials of its revolutionary eye care technology, aimed at FDA approval.
European startups
fromHarvard Gazette
4 months ago

How halt in funding hurts efforts to ensure safety of patients in medical research - Harvard Gazette

The freeze of federal research grants to Harvard disrupts critical oversight of medical studies, impacting the rights and safety of research participants.
Privacy professionals
Mental health
fromHarvard Gazette
4 months ago

FDA-approved smoking cessation pill helps break vaping habit - Harvard Gazette

Varenicline significantly increases smoking cessation success among teens and young adults compared to behavioral counseling alone.
Coronavirus
fromNature
4 months ago

A front-line antiviral drug disappoints against worrisome monkeypox strain

Tecovirimat, approved in Europe for mpox, showed limited effectiveness in hastening recovery in human clinical trials.
#brexit
fromwww.theguardian.com
4 months ago
UK news

Children with cancer cannot wait': the human cost of clinical trial delays after Brexit

Brexit is complicating cancer trials in the UK, raising costs and causing delays, preventing patients from accessing new treatments.
The eSMART trial faces significant logistical challenges post-Brexit.
fromwww.theguardian.com
4 months ago
UK news

NHS cancer patients denied life-saving drugs due to Brexit costs, report finds

Brexit is negatively impacting access to life-saving cancer drugs for UK patients.
UK news
fromwww.theguardian.com
4 months ago

Children with cancer cannot wait': the human cost of clinical trial delays after Brexit

Brexit is complicating cancer trials in the UK, raising costs and causing delays, preventing patients from accessing new treatments.
The eSMART trial faces significant logistical challenges post-Brexit.
Wearables
fromwww.nytimes.com
5 months ago

What to Know About Eli Lilly's Daily Pill for Weight Loss

Eli Lilly's orforglipron offers a potential oral treatment for obesity and diabetes, expanding access beyond current injected options.
fromNature
5 months ago

Japan's big bet on stem-cell therapies might soon pay off with breakthrough therapies

"After nearly two decades of hard work and setbacks, many say that Japan is on the cusp of bringing these therapies to market."
Alternative medicine
fromSilicon Valley Journals
5 months ago

A biotech company which developing therapies for orphan diseases raises $115M in funding

Glycomine's progress towards delivering the first disease-modifying therapy for a rare genetic disorder was bolstered by a $115 million Series C funding round.
Startup companies
#heart-failure
fromwww.theguardian.com
5 months ago
London startup

British hospitals introduce treatment for heart failure that cuts deaths by 62%

New treatment approach for heart failure patients dramatically reduces mortality and hospital readmissions.
fromtime.com
5 months ago

Pfizer Ends Development of Its Obesity Pill

Pfizer's decision to halt danuglipron development underscores the risks and complexities involved in creating new obesity treatments, particularly after significant financial investment and testing phases.
Wearables
fromwww.bbc.com
5 months ago

Skin cancer patients could join vaccine project

Thankfully I was still quite fit and since I've been on it, my tumours have all shrunk. Every time I go for a scan they seem to be shrinking, which is very exciting.
Cancer
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