#blood-brain-barrier

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fromNews Center
1 week ago

Experimental Drug Shows Promise for Rare Genetic Disorder - News Center

Mucopolysaccharidosis type II (MPS II), or Hunter syndrome, is a rare genetic disorder primarily affecting boys, caused by a deficiency in the enzyme needed to break down sugar molecules. This harmful buildup in cells and tissues impacts multiple body systems, causing frequent infections, organ enlargement and developmental disabilities. Management involves supportive care and enzyme replacement therapy, as there is currently no cure,
Medicine
fromNews Center
2 weeks ago

Post-Stroke Injection Protects the Brain in Preclinical Study - News Center

When a person suffers a stroke, physicians must restore blood flow to the brain as quickly as possible to save their life. But, ironically, that life-saving rush of blood can also trigger a second wave of damage - killing brain cells, fueling inflammation and increasing the odds of long-term disability. Now, in a study published in the journal Neurotherapeutics, Northwestern University scientists have developed an injectable regenerative nanomaterial that helps protect the brain during this vulnerable window.
Medicine
Medicine
fromMail Online
2 months ago

Breakthrough as 40-year-old drug is revamped to destroy cancer cells

Patented mebendazole polymorph C reaches tumors, including brain tumors, at higher concentrations and shows stronger anticancer effects, especially when combined with efflux inhibitors.
Alternative medicine
fromNatural Health News
2 months ago

"Supercharged" vitamin K derivatives offer new hope for neurodegenerative diseases

Synthetic vitamin K analogues, especially compound 7, strongly activate mGluR1 signaling and more potently induce neural progenitor differentiation, showing promise for neuron regeneration therapies.
#alzheimers
Medicine
fromNature
4 months ago

Repeated head trauma causes neuron loss and inflammation in young athletes - Nature

Repetitive head impacts produce early neuroinflammation, blood-brain barrier breakdown, astrocytic and white matter pathology that precede p-tau deposition and drive early CTE.
Science
fromNature
5 months ago

Transport vehicle delivers antibodies to the brain

A TfR-targeted shuttle delivers anti–amyloid-β antibody across the blood–brain barrier, improving brain distribution and safety in mice.
Medicine
fromPsychology Today
5 months ago

The Brain's Border Wall and Psychiatric Illness

A leaky blood-brain barrier can cause psychiatric illness; boosting mitochondrial function in barrier cells repairs the barrier and relieves impaired social interaction.
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