In mid-August 1951, hundreds of respectable citizens went mad in Pont-Saint-Esprit, a small town in the south of France, caused by ergot fungus in grain.
The ingestion of ergot alkaloids, mycotoxins found in grains, resulted in severe hallucinations and long-lasting trauma for over 300 residents.
Dr. Albert Hofmann, who discovered LSD, synthesized it from ergot during trials to create a cardiocirculatory stimulant, leading to unexpected psychedelic properties.
The effects of ergot can linger in the body after ingestion, impacting consciousness even when the mycotoxin is no longer perceptible.
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