The VITAL randomized controlled trial has provided evidence that vitamin D supplementation contributes to the maintenance of telomere length, which is crucial for cellular protection against aging and disease. This trial, co-led by researchers from Mass General Brigham, followed over 1,000 participants aged 50 and older for five years, showing significant benefits beyond telomere preservation, including reduced inflammation and lower risks of chronic diseases such as advanced cancer. This study represents a milestone in understanding the role of vitamin D in biological aging.
VITAL is the first large-scale and long-term randomized trial to show that vitamin D supplements protect telomeres and preserve telomere length.
This is of particular interest because VITAL had also shown benefits of vitamin D in reducing inflammation and lowering risks of selected chronic diseases of aging.
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