The research indicates that fat cells can retain a 'memory' of obesity through lasting changes in their epigenome, making it difficult for individuals to maintain weight loss.
Study co-author Laura Hinte emphasizes the importance of long-term care for those trying to lose weight, stating, 'it means that you need more help, potentially. It's not your fault.'
Hyun Cheol Roh describes the findings as significant, stating that they reveal what happens at the molecular level in fat cells, shedding light on the obesity reversal process.
The study reveals that even after weight-loss surgery, the body's fat cells show differences in gene activity between those who had obesity and those who did not.
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