The device's design is analogous to a continuous glucose monitor that sits on your arm and measures levels right beneath your skin. You can see that your glucose levels are increasing in real time. But then maybe you take your insulin, and your glucose goes back down. You need to be able to measure trends in the wrong direction and trends in the right direction. It's the same with proteins in inflammation. We need to track fluctuations to get a full picture of what's happening in the body.
In proof-of-concept experiments, the sensors accurately and sensitively measured protein biomarkers of inflammation in diabetic rats. The work lays the foundation for the real-time management and prevention of acute and chronic conditions through the tracking of critical proteins, such as cytokines in inflammation, protein biomarkers in heart failure and many others.
#implantable-device #protein-monitoring #real-time-health-tracking #inflammation #biomedical-engineering
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