Most activities in cells depend on proteins folding into specific 3D shapes, crucial for cell functions and interactions with other molecules.
AlphaFold, developed by DeepMind, revolutionized protein structure prediction by accurately determining complex 3D shapes, with the latest version handling various protein interactions.
Evolutionary constraints on proteins inform AlphaFold's predictions, identifying essential parts for function by comparing sequences from different species to determine consistent locations in the structure.
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