"In the team's second straight blowout loss, San Francisco may have also lost running back McCaffrey to a season-ending knee injury-less than a month after he returned to the starting lineup. Now this offense will be playing do-or-die football without one of its most explosive players... the defense is playing some of its worst football in the Kyle Shanahan era. This year went from unlucky to terrible quickly, and the worst may be yet to come."
"The 49ers have become an injury-riddled, unrecognizable mess on both sides of the ball. They are just missing too many key pieces even with Brock Purdy back. They are down to flashing a tiny bit of last year's NFC champions."
"It's time to stick a fork in the San Francisco 49ers. They suffered another damaging loss that dropped them further into last place in their division, and a playoff spot is looking increasingly unlikely as injuries continue to plague the team."
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