With Deebo Samuel and Christian McCaffrey sidelined, the 49ers may lean on Jacob Cowing and Eric Saubert to fill vital roles in the offense.
Jacob Cowing's versatility could provide the 49ers with the dynamic plays they need, as he is adept at running sweeps and screens, making him a valuable asset.
If the 49ers resort to a more physical style of play due to injuries, Eric Saubert's role might increase, possibly leading to his critical involvement in the offense.
Despite facing a loss, the 49ers need to adapt their strategy in the absence of key players, making adjustments to their offensive game plan.
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