Coach Kyle Shanahan said the following six players were being ruled out from appearing in the Week 18 game: running back Christian McCaffrey (calf), defensive tackle Arik Armstead (foot, knee), tight end Ross Dwelley (ankle), cornerback Ambry Thomas (hand), and starting safeties Ji'Ayir Brown (knee) and Tashaun Gipson (quadriceps).
Teams are allowed to suit up only 48 active players, as long as they have eight offensive linemen active. Pro Bowl left tackle Trent Williams is expected to play, 49ers general manager John Lynch said Friday morning during his weekly appearance on KNBR.
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