George Kittle is doubtful for Sunday’s game against the Los Angeles Rams due to hamstring soreness, joining other key 49ers offensive players on the sidelines.
Kittle's absence will likely shift the 49ers' strategy; they are expected to rely more on fullback Kyle Juszczyk and backup tight ends for the game plan.
Brandon Aiyuk is struggling to find his rhythm with quarterback Brock Purdy, averaging only three catches for 35 1/2 yards in the previous games.
With Kittle out, Eric Saubert may play a vital role in the passing game, having already been involved more than last season's tight ends.
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