The San Francisco 49ers face significant injury struggles, with key players like Deebo Samuel and Javon Hargrave missing practice ahead of their Week 4 matchup.
Despite the injuries, quarterback Brock Purdy participated fully in practice, easing concerns about his back soreness following Week 3, which is promising for the 49ers.
The participation report reveals major absences, notably Deebo Samuel and defensive tackle Javon Hargrave, while left tackle Trent Williams' illness adds more uncertainty to their week.
Limited participation from tight end George Kittle provides a glimmer of hope for the 49ers as they navigate numerous injuries affecting their roster.
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