Scientists have engineered nasal bacteria to deliver hormones to the brains of obese mice, resulting in weight loss, as reported in Cell. This innovative approach is being explored to enhance drug delivery in various areas of the body, utilizing the relatively unexplored nasal microbiome. The studies aim to circumvent barriers that typically prevent drugs from reaching targeted sites, such as the brain's protective barrier. Experts believe that if successful, these methods could offer effective therapies with fewer side effects for patients.
One of the latest examples of efforts to harness bacteria for drug delivery is via engineered nasal bacteria delivering hormones to obese mice, showing promise for future therapies.
Using nasal bacteria to transport drugs highlights a novel approach in biomedicine, demonstrating improved delivery methods that could minimize side effects for patients undergoing treatment.
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