"Think of this as a five-star anti-ageing spa for the old egg," says Rong Li, a cell biologist at NUS, highlighting the profound rejuvenating effects of young follicles on aged oocytes.
The latest study offers the 'first solid, strong evidence' that follicles can improve the quality of maturing eggs, indicating a significant breakthrough in understanding reproductive aging.
After replacing old oocytes with young ones in the prime follicles, they found that the quality of the oocytes significantly improved, revealing an important connection between follicle age and egg vitality.
Old oocytes, when developed in young follicles, showed dramatically fewer chromosomal abnormalities and enhanced mitochondrial function, suggesting that the environment plays a crucial role in egg quality.
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