Starfish possess a unique survival mechanism; when threatened, they can detach their own limbs through a neuropeptide response, allowing them to escape predation.
The neuropeptide ArSK/CCK1 is first identified as a key regulator of autotomy in animals, effectively promoting limb loss as a defense mechanism.
In experiments simulating predator attacks, starfish responded with limb detachment when pressure was applied at specific sites, confirming the neuropeptide’s role in this response.
This research opens new avenues for understanding limb autotomy in other species and highlights the intricate biology of starfish survival strategies.
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