In a world where there are infinite multiverses, one of those is going to be an anime multiverse. So Rick and Morty: The Anime is automatically canon because within their multiverse, almost anything could be canon.
This isn't a spinoff, this is [Sano's] reinterpretation of the characters and themes from the original. He had the freedom to interpret them how he wanted within the framework that was already laid down by the show.
Rick and Morty: The Anime is much more of an anime than it is a take on Rick and Morty. Gone are Rick's belches and the joke-a-minute pace. Instead, the dialogue is slower, deliberate, and deadly serious.
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