This reasonably comfortable win over Glasgow across the road from where the Calcutta Cup will be contested next month put the home team through to the last 16.
The news for Gregor Townsend worsened only 10 minutes in, when Scott Cummings, one of Scotland's locks, was forced off. He later appeared with his arm in a sling.
Better news was forthcoming in the form of Tuipulotu's replacement, Stafford McDowall, who also assumed the captaincy in the absence of Kyle Steyn.
Quins had already opened a 17-0 lead at that point with two tries in the first quarter and a Marcus Smith penalty.
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