An editorial expression of concern was issued regarding the data presented in Supplementary Figures 6 and 7 from a 2013 article on 53BP1's role in DNA damage repair. Issues identified include repetitive patterns in flow cytometry plots and similarity between 53BP1 and Flag lanes, indicating potential data manipulation. Although the integrity of the article's conclusions remains intact, readers are urged to interpret those results with caution. The authors are working on replicating the experiments, and the revised results will be provided in future publications.
The Editors would like to alert the readers that concerns have been raised regarding the data presented in Supplementary Figs. 6 and 7.
Although the affected figures do not alter the results or conclusions of the article, readers are advised to interpret these results with caution.
The first and corresponding authors are in the process of re-doing these experiments, the results of which will be reported elsewhere.
Alexandre Orthwein has not responded to any correspondence about this Editorial Expression of Concern.
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