The witches in question are, of course, the Bene Gesserit, the female religious order that secretly pulls as many of the Dune universe's strings as it can get its hands on.
After five episodes, Dune: Prophecy hasn't set up any particularly sympathetic characters or established a line between good and evil, even a fuzzy one.
It feels true both to the world created by Frank Herbert's books and to Dune: Prophecy's other source of inspiration, Game of Thrones.
Dune: Prophecy is set 10,000 years before the events of Dune. In that later timeline, the Bene Gesserit aren't just alive and well as the story opens.
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