People with schizophrenia and other disorders with psychosis symptoms often have difficulty forming and maintaining social connections. Most research on social difficulties that are a core feature of psychotic disorders has focused on brain areas involved in social processing. The role of brain areas involved in social motivation remains largely uncharted territory.
This study was in line with the principles of the NIMH Research Domain Criteria (RDoC) initiative. Researchers led by Amy Jimenez, Ph.D., at the University of California, Los Angeles, and William Horan, Ph.D., at the University of California, Los Angeles, and Karuna Therapeutics, aimed to uncover the underlying mechanisms that might explain why many people with psychotic disorders lack motivation to socialize.
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