"New findings from the University of Cambridge suggest that menopause is associated with changes in brain structure, along with higher levels of anxiety, depression, and sleep difficulties. Researchers found reduced grey matter volume in several important brain regions among women who had gone through menopause. The study, published in Psychological Medicine, also examined the effects of hormone replacement therapy (HRT). While HRT did not appear to prevent these brain or mental health changes, it was associated with a slower decline in reaction speed."
"Understanding Menopause and Its Symptoms Menopause marks the stage of life when a woman's menstrual periods permanently stop due to declining hormone levels. It most commonly occurs between ages 45 and 55 and is often accompanied by symptoms such as hot flushes, low mood, and disrupted sleep. Previous research has also linked menopause to changes in cognitive abilities, including memory, attention, and language."
Menopause is associated with reductions in grey matter volume across several important brain regions and with higher levels of anxiety, depression, and sleep difficulties. Hormone replacement therapy (HRT) did not fully prevent changes in brain structure or mental health, though HRT use correlated with a slower decline in reaction speed. Nearly 125,000 women were analyzed using health questionnaires and cognitive tests assessing memory and reaction time, with participants grouped by menopausal status and HRT use. About 15% of women in England received HRT in 2023. Findings link menopausal transition to measurable brain and mental-health differences.
Read at ScienceDaily
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