By 2050, it is projected that over 139 million people globally will be living with dementia, a notable increase from the existing 55 million. A new study from researchers at Karolinska Institutet and Sahlgrenska University Hospital indicates that dementia patients on antidepressants, particularly SSRIs, tend to experience faster cognitive decline over time. SSRIs are widely prescribed to treat depression by enhancing serotonin levels in the brain. This research is pivotal as it is the first systematic examination of long-term antidepressant effects on cognition in dementia patients, drawing attention to the need for judicious medication management in this demographic.
By 2050, the number of people with dementia globally will surpass 139 million, indicating a pressing need for effective treatments and understanding of cognitive declines associated with antidepressants.
We found that long-term use of SSRIs in dementia patients could lead to a quicker cognitive decline, highlighting the importance of careful medication management in this vulnerable population.
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