The research discovered that women with premature ovarian insufficiency (POI) are at a significantly higher risk—two to three times more—for severe autoimmune disorders compared to the general population.
The study, which includes health data from Finland's comprehensive registries, found that 5.6% of women with POI were diagnosed with at least one autoimmune disorder prior to their POI diagnosis and 12.7% afterward.
Following a cohort of almost 20,000 women for over 12 years, the findings bolster the hypothesis that autoimmune processes are pivotal in triggering premature ovarian insufficiency.
The odds of developing severe autoimmune diseases, particularly for issues like polyglandular autoimmune diseases, were alarmingly high—up to 26 times more for some women with POI who had no previous conditions.
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