
"While perhaps a dozen people worldwide have been declared free of the virus, those results haven't been replicated widely, and treatments for some involve continuing therapies or procedures, like stem cell and bone marrow transplants, that aren't feasible for widespread use. So far, there is no "magic bullet" to cure HIV for good. But scientists are making rapid progress on several fronts and say a cure is within reach. Here's a roundup of where the latest progress stands."
"A study from the Federal University of São Paulo (UNIFESP), published in August, details how a team of researchers in Brazil succeeded in eliminating HIV from a patient's body for 78 consecutive weeks with a "supertherapy", achieving the result with a combination of medications alone and without stem cell transplants or gene therapy. The study combined potent antiretroviral drugs with innovative compounds including auranofin, a gold salt, that were designed to both activate and eliminate viral reservoirs"
Nearly 45 years after the first HIV diagnosis, scientific efforts have advanced considerably while a universally applicable cure remains absent. A small number of people have been declared free of the virus, but those outcomes have not been widely replicated and some cures depend on procedures like stem cell or bone marrow transplants that are not feasible for broad use. No single "magic bullet" currently exists, yet multiple strategies are progressing. A team at the Federal University of São Paulo achieved 78 weeks of virus elimination in one patient using antiretrovirals combined with compounds such as auranofin that target and reduce viral reservoirs while stimulating immune clearance. Reduced viral load increases proximity to a durable cure, and emerging cellular approaches such as self-replicating CD8 cells are under investigation.
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