The Guardian view on ageing research: our lives have more distinct phases than we thought | Editorial
Briefly

The Guardian view on ageing research: our lives have more distinct phases than we thought | Editorial
"Ageing can feel remarkably sudden. One morning you awake to find new aches, or lapses in strength and memory that you could swear were not present just a few days prior. We do not literally age overnight, but as research is increasingly showing, we may not do so in a steady, linear path either. Over the past decade a multitude of studies have suggested that ageing at least for certain organs and bodily systems may actually consist of long periods"
"The latest study bolstering this view, published in Nature Communications, used a large number of brain scans to show that the structure and interconnectivity of the brain can be separated into five distinct eras, marked by turning points at nine, 32, 66 and 83. Of particular interest in this study is the identification of a very long adolescent phase from age nine to 32 in which brain connections appear to become stronger and more efficient a period that extends well into"
Ageing often follows long stable periods interrupted by inflection points of rapid biological change rather than a steady linear decline. Brain structure and interconnectivity separate into five distinct eras with turning points at ages nine, 32, 66 and 83. A prolonged adolescent phase from age nine to 32 shows strengthening and increased efficiency of brain connections, extending into traditional adulthood. Multiple organs show accelerated ageing around midlife with metabolic shifts near 44 and 60, skin passes through four ageing phases, and the adult immune system shows two phases. Omics datasets enable comprehensive molecular measurement, aiding these insights.
Read at www.theguardian.com
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