The skin is the organ most frequently affected by adverse drug reactions, with severe forms like TEN having a one-third fatality rate and significant implications for patient care.
Spatial omics, specifically deep visual proteomics, allows for a comprehensive molecular examination of skin tissues, shedding light on the complex mechanisms behind CADRs, particularly aiding in the understanding of TEN.
Despite technological advancements in profiling skin reactions, translating these findings into clinical applications poses significant challenges and remains an aspirational goal for modern medical practices.
The study of cutaneous adverse drug reactions highlights the need for deeper insights into patient-specific responses, improving therapeutic options and ensuring better outcomes for severe conditions like TEN.
#adverse-drug-reactions #skin-conditions #deep-visual-proteomics #therapeutic-interventions #clinical-research
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