"Green tea is an ancient beverage recognized for its medicinal and antioxidant properties. It has been widely studied for its beneficial effects on metabolic diseases, such as obesity and type 2 diabetes. Recent studies funded by FAPESP have deepened our understanding of the mechanisms of action of this infusion and revealed that green tea treatment reduced weight and significantly improved glucose sensitivity and insulin resistance in obese mice."
"Rosemari Otton led the studies from the Interdisciplinary Graduate Program in Health Sciences at Cruzeiro do Sul University in São Paulo, Brazil. The scientist, who has dedicated more than 15 years to green tea research, explains that her initial motivation came from curiosity about the truth behind the popular belief that the drink aids in weight loss. The results of her most recent study were published in the journal Cell Biochemistry & Function."
"To study the effects of green tea on obesity, the research team fed mice a high-calorie diet for four weeks, with both fat and what they call a "cafeteria diet," which mimics the Western diet. "We give them chocolate, filled cookies, dulce de leche, condensed milk... In other words, the same type of food that many people consume on a daily basis," says Otton. After this initial phase, the animals underwent the green tea experiment for another 12 weeks."
Green tea has medicinal and antioxidant properties and has been studied for effects on metabolic diseases including obesity and type 2 diabetes. Controlled experiments in obese mice fed high‑calorie and Western‑style "cafeteria" diets produced up to 30% body weight reduction and marked improvements in glucose sensitivity and insulin resistance after administration of standardized green tea extract. Mice received a 12‑week treatment while remaining on the high‑calorie diet, with extract delivered intragastrically at 500 mg/kg. Observed outcomes included targeted fat reduction and improved metabolic function, indicating potential as an adjunct natural therapy for obesity.
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