"Fred Ramsdell shared Monday's prestigious prize with Mary Brunkow of Seattle, Washington and Shimon Sakaguchi of Osaka University in Japan for their discoveries related to the functioning of the immune system. But the laureate's digital detox means the Nobel committee has been unable to reach him and break the news. Jeffrey Bluestone, a friend of Ramsdell's and co-founder of the lab, said the researcher deserves credit but he can't reach him, either."
"The three won the prize for research that identified the immune system's security guards, called regulatory T-cells. Their work concerns peripheral immune tolerance that prevents the immune system from harming the body, and has led to a new field of research and the development of potential medical treatments now being evaluated in clinical trials. Sakaguchi, 74, made the first key find in 1995, discovering a previously unknown class of immune cells that protect the body from autoimmune diseases."
Fred Ramsdell, Mary Brunkow and Shimon Sakaguchi won the Nobel Prize in Medicine for discoveries of regulatory T-cells and peripheral immune tolerance. Ramsdell has been unreachable while off-grid backpacking, prompting the Nobel committee and colleague Jeffrey Bluestone to try and contact him; Bluestone suggested Ramsdell may be backpacking in Idaho. The committee initially had difficulty reaching Brunkow because of the US West Coast time difference but eventually contacted her. Sakaguchi first identified the immune cell class in 1995; Brunkow and Ramsdell made a complementary discovery in 2001. The research underpins new clinical trials and therapeutic development.
Read at www.theguardian.com
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