Luke O'Neill: The next generation of weight-loss drugs is coming - and they will be cheaper and more effective
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Luke O'Neill: The next generation of weight-loss drugs is coming - and they will be cheaper and more effective
"Everyone has heard of the weight loss drug Ozempic. Other brands include Weg­ovy, Mounjaro and Zepbound. These are all basically the same and are based on a natural hormone called GLP-1. Your body makes GLP-1 after a meal and it makes you feel full, stopping you eating."
"It also helps your body absorb sugar. Taking the drugs has the same effect as natural GLP-1, so users lose weight because their appetite is lowered and they eat less. The drugs are also useful for people with type-2 diabetes because they lower blood sugar, which is high in diabetics."
Drugs such as Ozempic, Weg­ovy, Mounjaro and Zepbound derive from the hormone GLP-1. GLP-1 is produced after eating and signals fullness, reducing subsequent food intake. GLP-1 also aids the body's absorption of sugar. Pharmaceutical GLP-1 analogues replicate these effects, lowering appetite and causing weight loss by reducing calorie intake. GLP-1 drugs also reduce blood glucose levels, making them therapeutically useful for people with type-2 diabetes. The combined appetite suppression and blood-sugar lowering properties explain why the drugs are used for both weight management and diabetic glycaemic control.
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