"Lab-grown structure mimics the adrenal cortex, which produces the critical hormone called cortisol. For the first time, scientists have developed a laboratory-grown version of the adrenal cortex - the outer part of the adrenal gland, which produces hormones essential for regulating metabolism, stress and blood pressure. The 'organoid' could one day be used to develop treatments for disorders of the adrenal gland."
"The 'organoid' could one day be used to develop treatments for disorders of the adrenal gland."
A laboratory-grown adrenal cortex organoid has been created that mimics the outer adrenal gland and produces cortisol. The organoid generates hormones that regulate metabolism, stress responses and blood pressure. The model reproduces key adrenal cortex functions and provides a platform for studying adrenal physiology and disease mechanisms. The organoid enables drug testing and therapeutic development targeted at adrenal disorders. Future work must establish long-term functionality, immune compatibility, scalability and safety to support clinical translation and potential cell-based therapies or transplantation strategies.
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