"Doctors have launched a clinical trial of a 100 blood test for Alzheimer's disease in the hope of transforming diagnosis of the devastating condition in the NHS. More than 1,000 patients with suspected dementia are being recruited from memory clinics across the UK to see whether the test leads to faster and more reliable diagnoses and better care for those found to have the disease."
"While new drugs such as lecanemab and donanemab have been shown to slow the disease, they have a small effect and have been rejected for widespread use by the UK's National Institute for Health and Care Excellence (Nice). Hopes now ride on a second generation of Alzheimer's drugs that are being tested in clinical trials. Alzheimer's drugs work best when given in the early stages of the disease, before the brain has suffered major, irreversible harm."
A clinical trial is testing a £100 blood test for Alzheimer's to enable faster, more reliable diagnosis in NHS memory clinics. About 1,100 people with suspected dementia are being recruited from diverse geographic, ethnic and economic backgrounds, including those with other medical problems. The blood test measures p-tau217, a protein that reflects amyloid and tau pathology, and evidence indicates it can detect these hallmarks as accurately as PET scans and lumbar punctures. Only about 2% of patients currently receive gold-standard testing. Early detection would identify those who could benefit most from treatments as new drugs reach the clinic.
Read at www.theguardian.com
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