"On average, people who had not taken any antibiotics in the past eight years had about 350 unique bacterial species living in their gut, but those who had taken any antibiotics in that time frame had fewer. The level of microbial diversity also depended on which drug they had taken."
"Clindamycin, which is sometimes prescribed for skin and dental infections, was the most disruptive: each course taken in the year before stool sampling was linked to an average of 47 fewer detected species, as well as changes in abundance in almost 300 of the 1,340 species analyzed."
"Courses of fluoroquinolones, which are often prescribed for urinary tract infections and respiratory infections, and flucloxacillin, which is mainly prescribed for Staphylococcus aureus infections, both corresponded to an average of about 20 fewer species."
A Swedish study of nearly 15,000 adults examined how antibiotics affect gut microbiome composition by comparing stool samples with prescription records over eight years. People who had not taken antibiotics maintained approximately 350 unique bacterial species, while those with antibiotic exposure had fewer species. The impact varied by antibiotic type: clindamycin was most disruptive, reducing detected species by an average of 47 per course and altering abundance in nearly 300 species. Fluoroquinolones and flucloxacillin each reduced species by about 20 on average. Most antibiotics analyzed linked to decreased bacterial abundance, though some correlated with increases in certain bacteria.
Read at www.scientificamerican.com
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