
"Results of this study indicate that the association between acetaminophen use during pregnancy and neurodevelopmental disorders is a noncausal association. Birthing parents with higher acetaminophen use differed in many aspects from those with lower use or no use. Results suggested that there was not one single "smoking gun" confounder, but rather that multiple birthing parents' health and sociodemographic characteristics each explained at least part of the apparent association."
""Untreated fever, particularly in the first trimester, increases the risk of miscarriage, birth defects, and premature birth, and untreated pain can lead to maternal depression, anxiety, and high blood pressure," SMFM noted. With no clear evidence supporting a link between acetaminophen and autism, doctors highlight another fold in the issue: Acetaminophen is considered the safest pain reliever/fever-reducer during pregnancy. Nonsteroidal anti-inflammatory medications (also called NSAIDS), such as ibuprofen (Advil) and aspirin, can cause reduced blood flow, heart problems, and kidney problems in a fetus."
The association between acetaminophen use during pregnancy and neurodevelopmental disorders is noncausal. Birthing parents with higher acetaminophen use differed in many health and sociodemographic characteristics from those with lower use or no use. Multiple parental health and sociodemographic factors each explained at least part of the apparent association rather than one single confounder. Sibling-control analyses produced null results that indicate shared familial confounders but did not identify specific factors. Untreated or prolonged fevers during pregnancy are linked to increased autism risk and carry risks such as miscarriage, birth defects, premature birth, maternal depression, anxiety, and high blood pressure. Acetaminophen is considered the safest pain reliever during pregnancy, whereas NSAIDs can cause reduced fetal blood flow, heart problems, and kidney problems.
Read at Ars Technica
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