Alzheimer's Fully Reversed in Mice, Scientists Say

"A team of American scientists claim they have done something miraculous: they "cured" lab mice suffering from Alzheimer's disease, which has robbed more than seven million Americans, typically 65 years old and up, of their identity and cognitive ability. The researchers achieved this feat by administering the rodents with the powerful compound P7C3-A20, which they announced in a new paper in the journal Cell Reports Medicine."

""The key takeaway is a message of hope - the effects of Alzheimer's disease may not be inevitably permanent," said Andrew A. Pieper, the study's principal investigator and a CWRU neuroscience professor, in a statement about the research. "The damaged brain can, under some conditions, repair itself and regain function." This research is part of a growing wave of very promising lab studies that point to a tantalizing future where Alzheimer's and other neurological issues could be a thing of the past."

Scientists at Case Western Reserve University, University Hospitals, and the Louis Stokes Cleveland VA administered the compound P7C3-A20 to laboratory mice with Alzheimer's-like disease and observed reversal of cognitive deficits. Treated rodents showed restored function and indications of neuronal repair. Findings indicate that damaged brains can, under some conditions, repair themselves and regain function. Parallel laboratory work using other compounds and treatments has produced promising results. Advances in understanding genetic, environmental, and other triggers of Alzheimer's support prospects for personalized prevention and therapies. Some experts predict clinically meaningful treatments and earlier detection within five to ten years.

Read at Futurism