"I'm certainly confident that we're going to have a breakthrough within my career, and I have a good 10 to 15 years left. While antiretroviral (ARV) therapies are extending lives and keeping HIV at bay, and PrEP has the potential to effectively halt transmission of the virus, a cure has remained elusive. That's because the HIV virus itself is elusive, both co-opting the immune system and hiding from it."
"We're really kind of landing this effort with the progress we've made to date. If you think about it like landing a plane and you're going at 30,000 feet, and you're then going down towards the runway, and you're seeing the runway ahead, I think that we see the runway now much clearer than we did, say, five or 10 years ago, and it's been because of the investment that's been made."
Antiretroviral therapies and PrEP have transformed HIV into a manageable condition but have not achieved a cure because HIV hides in and subverts the immune system. Recent discoveries, increased investment, and targeted cure-directed research have clarified a path toward eradication. A single "magic bullet" is unlikely; a combination of complementary therapies will be necessary, mirroring the multi-drug approach of antiretroviral regimens. Optimism exists that breakthrough strategies employing immune modulation, reservoir targeting, and combination interventions could achieve durable remission or elimination within the next decade to decade-and-a-half. Progress in clinical trials and laboratory studies is improving understanding of viral reservoirs and immune control.
Read at LGBTQ Nation
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