"Scientists have long recognized that conditions affecting the body can also influence the brain. Issues such as obesity, high blood pressure and insulin resistance place strain on the body's metabolic and vascular systems. Over time, this buildup of stress can accelerate cognitive decline and raise the likelihood of Alzheimer's disease. Researchers at Arizona State University, working with partners at several institutions, now report that these effects may appear much earlier than expected."
"The study uncovered another important finding. Many of the young adults showed unusually low blood levels of choline, a nutrient essential for supporting liver health, regulating inflammation and protecting long-term brain function. "This research adds to the growing evidence that choline is a valuable marker of metabolic and brain dysfunction -- and reinforces the importance of sufficient daily intake, as it is essential for human health,""
Researchers at Arizona State University and partner institutions identified biological markers in young adults with obesity that indicate inflammation, liver strain and early neuronal injury. These biomarker patterns resemble those observed in older adults with cognitive impairment. Many participants exhibited unusually low blood choline, a nutrient required for liver health, inflammation regulation and long-term brain protection. Reduced choline levels have been linked to anxiety, memory impairment and broader metabolic dysfunction. The combination of early biomarker shifts and low choline in young adults suggests the initial development of processes that could increase long-term cognitive risk and vulnerability to neurodegenerative disease.
Read at ScienceDaily
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