Manchester United host Burnley aiming for their first Premier League win of the 2025/26 season. Ruben Amorim faces intensified pressure after a home defeat to Arsenal, a draw at Fulham and an EFL Cup exit at fourth-tier Grimsby Town. Lisandro Martinez remains sidelined with a long-term knee injury while Noussair Mazraoui is close to a bench return. Benjamin Sesko drops to the bench after starting at Grimsby following a £74m move from Leipzig. Altay Bayindir continues as the league goalkeeper. Burnley have multiple injury absences including Jordan Beyer, Connor Roberts and Zeki Amdouni, with Bashir Humphreys starting against Derby.
United centre-back Lisandro Martinez is recovering from a long-term knee injury and wideman Noussair Mazraoui is close to a return from the bench. Striker Benjamin Sesko made his first start in the defeat at Grimsby following the Slovenia international's £74 million arrival from Leipzig but is back on the bench. Andre Onana replaced Altay Bayindir in goal at Blundell Park but the Turkiye international has been ever-present in the league so far and continues that run.
Man United starting XI: Altay Baynidir, Matthijs De Ligt, Leny Yoro, Luke Shaw, Amad Diallo, Casemiro, Bruno Fernandes, Diogo Dalot, Mason Mount, Bryan Mbeumo, Matheus Cunha Man United substitutes: Onana, Dorgu, Heaven, Maguire, Mazraoui, Mainoo, Ugarte, Sesko, Zirkzee Burnley lineup vs Manchester United Burnley centre-back Jordan Beyer, right-back Connor Roberts and midfielder Zeki Amdouni are out with knee injuries. Winger Manuel Benson is recuperating from an Achilles tendon issue but new centre-back Bashir Humphreys started against Derby, as did forward Arm
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