Sadiq Khan will join regional mayors Andy Burnham and Steve Rotheram in giving evidence at the Covid-19 inquiry later.
Various witnesses have expressed concern about his performance as health secretary, with the inquiry hearing that the country's most senior civil servant at the time, Lord Sedwill, wanted Mr Hancock sacked.
The mayors will likely be questioned about engagements with the Government during the crisis, as lockdowns and restrictions were imposed across the country.
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