The Plasma Incinerator is arguably one of the best guns to use in the game. Even though its firepower isn't the highest, you can charge it up to do a significant amount of damage.
The Heavy Bolt Rifle is a light machine gun. Its firepower is surprisingly low for its heft, but it makes up for it in speed and range, which is ideal when you find yourself fighting large hordes.
The Melta Rifle is one of the strongest weapons to use in the game, with the highest firepower, capable of killing anything within two rounds.
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