On October 2, the Nobel Assembly at Karolinska Institutet announced that Hungarian-American biochemist Katalin Karikó and American immunologist Drew Weissman were awarded the 2023 Nobel Prize in Physiology or Medicine for their discoveries related to modified messenger ribonucleic acid (mRNA) for use in vaccines.
After failing to attract substantial grant funding for her work, Karikó chose to take a pay cut and remain at the University of Pennsylvania as an adjunct professor in order to continue her research.
mRNA vaccines were not an effective option until the pioneering work of these two scientists, one of whom faced considerable rejection while laying the foundation that answered one of the world's greatest public health crises.
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