'Splice' delves into the complexities and dark realities of genetic experimentation amid a world reshaped by ideas from the Human Genome Project. Highlighting the moral ambiguities faced by scientists, the film captures their descent into horror as they create an animal-human hybrid, Dren, who embodies both beauty and danger. Through shocking developments, such as Dren's changing forms, the film raises unsettling questions about the human condition and the potential consequences of genetic manipulation, leaving audiences with a chilling sense of unease that mirrors real-world anxieties in biotechnology.
If anything, it may have tapped into them a little too well. Splice is brilliant in its barrage of discomfort, rarely allowing its viewers a bit of respite.
The hybrid proves to be fractious, not just in personality, but physically. Dren surprises her "parents" by being amphibious, carnivorous, able to sprout wings, and eventually able to change her sex.
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