Clade I mpox is concerning due to its higher mortality rate and severity of the disease. The CDC indicates it has historically caused more severe outcomes.
Health officials warn that Clade I has a higher case fatality rate and results in more severe infections than the previously concerning Clade II variant.
The recent WHO declaration underlines the risk of Clade I mpox potentially spreading beyond Africa, raising alarms about a more virulent strain.
With over 99,500 cases of Clade II mpox found globally, concern is now shifting to Clade I, which is causing outbreaks in the DRC.
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