A study published in JAMA Cardiology suggests that commonly used biomarkers for predicting heart failure risk in the general population may not be effective for women postpartum, particularly those with histories of hypertension and diabetes during pregnancy. Research led by Dr. Priya Freaney analyzed NT-proBNP levels in over 4,000 individuals and found that complications like preeclampsia and gestational diabetes do not equate to elevated NT-proBNP levels years later, indicating a disconnect between expected heart disease risk and actual biomarker readings after pregnancy. This calls for revised screening approaches for women experiencing these complications.
We know that features of complicated pregnancies can impact a woman's heart disease risk decades later.
The findings of the study really surprised us because the individuals who had hypertensive disorders of pregnancy and gestational diabetes had lower rates of NT-proBNP.
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