Christina Applegate reveals she is largely confined to bed due to multiple sclerosis

"I tell myself, Just get her there safely and get home so you can get back into bed.' And that's what I do. MS is an autoimmune disease that occurs when the immune system begins to attack the sheath that protects nerve fibres, making it difficult for the brain to communicate with the rest of the body. It often makes it more challenging to walk and move, and for some leads to paralysis in the legs."

"My life isn't wrapped up with a bow, Applegate said. People's lives, sorry for lack of a better term, fucking suck sometimes. So I'm being as honest and raw as I possibly can. We all have come from somewhere, some places more painful than others, and it's what you do with it, I guess. This is not an inspirational book, by any means. But it can inspire."

"I see her look at me when I'm in bed and can't quite move, or I want to go say goodnight to her in her room, but I can't quite get down the hallway for whatever reason that my legs aren't working that day mommy can't do all the things that she use"

Christina Applegate, 54, revealed that multiple sclerosis has severely limited her mobility, confining her mostly to bed due to movement-related pain. Despite her condition, she maintains a routine of taking her 15-year-old daughter Sadie to school, describing it as their only private time together and her favorite daily activity. Multiple sclerosis is an autoimmune disease where the immune system attacks nerve fiber sheaths, impairing brain-body communication and causing movement difficulties. The disease predominantly affects women, is rarely fatal, but typically reduces life expectancy by five to ten years. Applegate's upcoming memoir, You With the Sad Eyes, explores her childhood in Los Angeles and her mother's struggles with addiction and abusive relationships. She emphasizes the memoir's raw honesty rather than inspirational tone, acknowledging that life's difficulties shape who people become.

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