"We realized this gene may be also important for exercise and if so, we should be able to detect a similar physiological effect in flies," said Lee.
Flies with too much autophagy had massive cell death leading to visible degeneration of the eye. Inactivating Idit gene restored the normal eye structure, indicating that Idit gene is involved in the autophagy process.
Previous research has shown irisin to be an important hormone involved in producing musculoskeletal and other benefits of exercise in mammals, as well as playing a role in adaptation to cold temperatures.
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